What PROGRESSIVE SCLEROSING POLIODYSTROPHY means: Progressive Sclerosing Poliodystrophy - Alpers' disease is a rare, genetically determined disease of the brain that causes progressive degeneration of grey matter in the cerebrum. The first sign of the disease usually begins early in life with convulsions. Other symptoms are developmental delay, progressive mental retardation, hypotonia (low muscle tone), spasticity (stiffness of the limbs), dementia, and liver conditions such as jaundice and cirrhosis that can lead to liver failure. Optic atrophy may also occur, often causing blindness. Researchers believe that Alpers' disease is caused by an underlying metabolic defect. Some patients have mutations in mitochondrial DNA. Researchers suspect that Alpers' disease is sometimes misdiagnosed as childhood jaundice or liver failure, since the only method of making a definitive diagnosis is by autopsy or brain biopsy after death.
- Definition Paroxysmal Hemicrania:
- Dictionary Hemicrania - is a rare form of headache that usually begins in adulthood. Patients experience severe throbbing, claw-like, or boring pain usually on one side of the face; in, around, or behind the progressive sclerosing poliodystrophy definition.
- Definition Periodic Paralyzes:
- Dictionary Familial periodic paralyzes are a group of inherited neurological disorders caused by mutations in genes that regulate sodium and calcium channels in nerve cells. They are characterized by episodes progressive sclerosing poliodystrophy explain.
- Definition Prosopagnosia:
- Dictionary Prosopagnosia is a neurological disorder characterized by the inability to recognize faces. Prosopagnosia is also known as face blindness or facial agnosia. The term prosopagnosia comes from the progressive sclerosing poliodystrophy what is.
- Definition Postinfectious Encephalomyelitis:
- Dictionary Encephalomyelitis - Acute disseminated encephalomyelitis (ADEM) is characterized by a brief but intense attack of inflammation in the brain and spinal cord that damages myelin - the protective progressive sclerosing poliodystrophy meaning.
