What INCLUSION BODY MYOSITIS means: Inclusion Body Myositis - Sporadic inclusion body myositis (sIBM) is an inflammatory muscle disease, characterized by slowly progressive weakness and wasting of the distal and proximal muscles, most apparent in the muscles of the arms and legs. Because sIBM affects different people in different ways and at different rates, there is no "textbook case." During the course of the illness, the patient's mobility is progressively restricted as it becomes hard for him or her to bend down, reach for things, walk quickly and so on. Many patients say they have balance problems and fall easily.
- Definition Infantile Neuroaxonal Dystrophy:
- Dictionary Neuroaxonal Dystrophy - INAD is caused by an abnormal build-up of substances in the nerves throughout the brain and body, which prevents them working properly. These deposits (sometimes called inclusion body myositis.
- Definition Infantile Refsum Disease:
- Dictionary Disease - is a disorder characterized by the reduction or absence of peroxisomes in the body and by the accumulation of phytanic acid in blood plasma and tissue. Infantile Refsum disease is one of a inclusion body myositis.
- Definition Infantile Hypotonia:
- Dictionary or severely reduced muscle tone (the amount of tension or resistance to movement in a muscle), is seen primarily in children. It is not the same as muscle weakness but it can co-exist with muscle inclusion body myositis.
- Definition Inflammatory Myopathies:
- Dictionary Myopathies - is a term that defines a group of muscle diseases involving inflammation and degeneration of skeletal muscle tissues. Inclusion body myositis (IBM) mainly affects individuals over the inclusion body myositis.