What PRIMARY LATERAL SCLEROSIS means: Primary Lateral Sclerosis - (PLS) is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles. PLS belongs to a group of disorders known as motor neuron diseases. Motor neuron diseases develop when the nerve cells that control voluntary muscle movement degenerate and die, causing weakness in the muscles they control. Onset of PLS usually occurs after age 50. Symptoms may include difficulty with balance, weakness and stiffness in the legs, and clumsiness. Other symptoms may include spasticity (sudden, involuntary muscle spasms) in the hands, feet, or legs; foot dragging, and speech problems due to involvement of the facial muscles. The disorder usually begins in the legs, but it may also start in the tongue or the hands.
- Definition Progressive Multifocal Leukoencephalopathy:
- Dictionary Multifocal Leukoencephalopathy - (PML) is caused by the reactivation of a common virus in the central nervous system of immune-compromised individuals. Polyomavirus JC (often called JC virus) is primary lateral sclerosis definition.
- Definition Pervasive Developmental Disorders:
- Dictionary Developmental Disorders - The diagnostic category of pervasive developmental disorders (PDD) refers to a group of disorders characterized by delays in the development of socialization and primary lateral sclerosis explain.
- Definition Parry-Romberg:
- Dictionary Parry-Romberg syndrome is a rare disorder characterized by slowly progressive deterioration (atrophy) of the skin and soft tissues of half of the face (hemifacial atrophy), usually the left side. It primary lateral sclerosis what is.
- Definition Postural Hypotension:
- Dictionary Hypotension - Orthostatic hypotension is a sudden fall in blood pressure that occurs when a person assumes a standing position. It may be caused by hypovolemia (a decreased amount of blood in the primary lateral sclerosis meaning.
