What GLOBOID CELL LEUKODYSTROPHY means: Globoid Cell Leukodystrophy - or Krabbe disease is a rare, inherited degenerative disorder of the central and peripheral nervous systems. It is characterized by the presence of globoid cells (cells that have more than one nucleus), the breakdown of the nerve's protective myelin coating, and destruction of brain cells. Krabbe disease is one of a group of genetic disorders called the leukodystrophies. There is no cure for Krabbe disease. Results of a very small clinical trial of patients with infantile Krabbe disease found that children who received umbilical cord blood stem cells from unrelated donors prior to symptom onset developed with little neurological impairment.
- Definition Gerstmann-Straussler-Scheinker Disease:
- Dictionary Straussler-Scheinker Disease - In adults, the syndrome may occur after a stroke or in association with damage to the parietal lobe. In addition to exhibiting the above symptoms, many adults also globoid cell leukodystrophy definition.
- Definition Glycogen Storage Disease:
- Dictionary Disease - (glycogenosis, dextrinosis) is any one of several inborn errors of metabolism that result from enzyme defects that affect the processing of glycogen synthesis or breakdown within muscles globoid cell leukodystrophy explain.
- Definition Gaucher'S Disease:
- Dictionary Disease - is the most common of the lysosomal storage diseases. It is caused by a deficiency of the enzyme glucocerebrosidase, leading to an accumulation of its substrate, the fatty substance globoid cell leukodystrophy what is.
- Definition Gangliosidoses:
- Dictionary The GM1 gangliosidoses are caused by a deficiency of beta-galactosidase, with resulting abnormal storage of acidic lipid materials in cells of the central and peripheral nervous systems, but globoid cell leukodystrophy meaning.
